Endocrine Abstracts

Introduction: Amiodarone induced thyrotoxicosis (AIT) occurs in 5–10% of patients and may occur at any time throughout the course of treatment including months after discontinuation. Two distinct forms of AIT are distinguished and treated differently. Iodine-induced hyperthyroidism, typically seen in patients with underlying thyroid disease, is referred to as typ1 AIT and treated with high doses of thionamide antithyroid drugs and perchlorate. Type 2 AIT is a destructive ...

Introduction: Generously supported by IPSEN)-->Acquired isolated ACTH deficiency with normal secretion of the remaining pituitary hormones is a rare condition in the absence of exposure to exogenous glucocorticoids. The aetiology is assumed to be autoimmune in most adult cases with traumatic brain injury and radiation exposure being rare causes. Pituitary transcription factor mutations may be identified in congenital and childhood on...